Also known as: Brain attack
Will's father Ray presents with confusion, inability to recall the month, and sluggish eye movements, prompting concern for a possible stroke and urgent MRI. His case creates conflict when FBI agents want to delay his medical care for a surveillance operation.
Bernie, Emily's boyfriend, has pancreatitis requiring ongoing drain care and glucose monitoring. Ethan provides discharge instructions as Bernie and Emily prepare to leave for Las Vegas.
Also known as: Manic depression
Claire, a pregnant bipolar patient previously treated by Dr. Manning, presents in acute mania after her Quetiapine dose was reduced for pregnancy safety. Her altered mental state complicates emergency obstetric care during the hospital lockdown, leading to concerns about her ability to care for the baby.
Also known as: Abruption
Claire suffers a placental abruption after her bicycle accident, causing significant bleeding and requiring emergency cesarean section. Dr. Manning and Dr. Charles are forced to perform the delivery in an orthopedic hallway during the hospital lockdown without proper surgical equipment.
Also known as: Ruptured spleen
Derek presents with left upper quadrant pain after a motor vehicle collision, found to have a splenic tear with ongoing hemorrhage. When the bleeding doesn't stop and he's trapped in the OR during lockdown, Dr. Rhodes and Dr. Bekker perform an emergency splenectomy with Ava donating blood directly to the patient.
Also known as: Cyanide poisoning
Jacob Patrick releases cyanide gas in the ED as an act of revenge for his wife's death, exposing himself and multiple staff members including Dr. Choi. The mass casualty event drives the central plot, causing a Code Orange lockdown and multiple patients in severe respiratory distress requiring hydroxocobalamin treatment.
Also known as: Stomach ulcer
Will presents with hematemesis (bloody vomit) initially thought to be from cyanide exposure, but is diagnosed with a peptic ulcer. The diagnosis hints at underlying stress and secrets Will is keeping from Natalie.
Also known as: Severe allergic reaction
Referenced case of Jacob Patrick's wife who died a year prior from anaphylaxis despite receiving standard treatment with antihistamines, steroids, epinephrine, and CPR. Her death motivates Patrick's revenge attack on the ED.