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Chicago Med

Chicago MedNBC

Season 4, Episode 22

10 medical diagnoses portrayed

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Also known as: Floppy heart valve

Endocarditis riskMitral regurgitation

Bonnie Rush, wife of cochlear implant patient Peter, presents with a systolic heart murmur. Diagnosed with mitral valve prolapse associated with her hearing loss (Usher Syndrome). Dr. Latham performs minimally invasive surgical repair to prevent progression to heart failure and endocarditis.

Chicago Med — S04E22Patient: Bonnie Rush

Also known as: Brain tumor

Focal edemaMidline shiftMotor weakness

Delmar Brendl, patient with anxiety disorder, presents with weakness and headaches. CT and MRI reveal a frontoparietal convexity meningioma causing his symptoms. Undergoes awake craniotomy due to tumor location, with Dr. Charles providing psychological support throughout the difficult procedure.

Chicago Med — S04E22Patient: Delmar Brendl

Also known as: Severe allergic reaction

Airway closureTongue swellingRespiratory failure

Henry Wilks initially presents with hives from allergic reaction, later develops life-threatening anaphylaxis after eating roast beef sandwich. Requires emergency intubation. Diagnosed with alpha-gal syndrome from lone star tick bite during fishing trip in Kentucky, causing newly developed meat allergy.

Chicago Med — S04E22Patient: Henry Wilks

Also known as: Underdeveloped left heart

Extensive adhesions from previous surgeryRight atrial tearLow oxygen saturation

Infant Sophie undergoes Glenn procedure (second stage palliative surgery for HLHS) to improve oxygenation and reduce pulmonary artery pressure. Surgery complicated by extensive adhesions causing right atrial tear requiring emergent bypass. Rhodes and Latham successfully complete bilateral anastomosis despite challenges.

Chicago Med — S04E22Patient: Sophie
Recurring storyline

Also known as: Breast cancer spread to kidney

Kidney metastasisKidney failureUremia

Sydney Hawkins, Maggie's kidney transplant recipient, develops kidney failure from what appears to be rejection but is actually a tumor. Pathology reveals the tumor is metastatic breast cancer originating from Maggie herself, transmitted via the donated kidney. Maggie faces devastating diagnosis of previously undetected metastatic breast cancer.

Chicago Med — S04E22Patient: Maggie Lockwood
Recurring storyline

Also known as: Anxiety disorder

Panic attacksClaustrophobia

Delmar Brendl has been treated by Dr. Charles for generalized anxiety disorder and panic attacks. His psychiatric condition complicates his awake brain surgery, requiring intensive psychological support from Dr. Charles throughout the procedure.

Chicago Med — S04E22Patient: Delmar Brendl

Also known as: Early-onset Alzheimer's

Wandering behaviorConfusionRisk of harm

Joanie Wilks has Alzheimer disease and lives with her husband Henry and his girlfriend Roxanne. During Henry's medical crisis, she wanders into traffic and nearly gets hit by cars, highlighting the challenges of her condition and the unconventional living arrangement.

Chicago Med — S04E22Patient: Joanie Wilks

Also known as: Insulin poisoning

Sudden deathCardiac arrhythmia

Autopsy reveals Connor's father Cornelius Rhodes died from synthetic insulin overdose administered in the hospital, not from natural causes. Death ruled suspicious, suggesting murder rather than the expected post-surgical complication.

Chicago Med — S04E22Patient: Cornelius Rhodes
Recurring storyline
Urticariasupporting

Also known as: Hives

Henry Wilks initially presents with generalized hives/rash discovered upon waking. Treated with antihistamines (Benadryl and Zantac). The hives are the first manifestation of his developing severe meat allergy from tick bite.

Chicago Med — S04E22Patient: Henry Wilks

Also known as: Meat allergy from tick bite

Anaphylaxis to mammalian meat

Henry Wilks diagnosed with alpha-gal syndrome caused by lone star tick bite during recent fishing trip in Kentucky. The condition causes delayed allergic reactions to mammalian meat, explaining his hives and subsequent life-threatening anaphylaxis to roast beef.

Chicago Med — S04E22Patient: Henry Wilks