
Also known as: Kidney injury from bus accident
Kate is impaled by rebar through the abdomen in a school bus crash, suffering severe kidney damage with bleeding into the belly. Dr. Marcel performs emergency surgery and removes the damaged kidney.
Also known as: Neck injury from rebar
Henry is impaled through the neck by rebar in the bus crash, injuring his jugular vein and later developing an expanding hematoma that compresses his airway. Dr. Marcel performs carotid artery reconstruction surgery.
Also known as: Heart valve infection
Mike, a heroin addict treated at the safe injection site, has recurrent endocarditis that has destroyed two heart valves. He develops severe aortic regurgitation and atrial fibrillation, requiring emergency cardioversion and valve replacement surgery after psychiatric evaluation.
Also known as: EVALI
Alice, a 12-year-old from the bus crash with rib fractures, develops progressive respiratory failure from pre-existing EVALI (vaping-related lung injury) that was exacerbated by the accident. She requires intubation with uncertain prognosis.
Also known as: Blood cancer
Gary is a leukemia patient scheduled for bone marrow transplant whose donor becomes unavailable due to fever. His anemia causes dangerous heart rhythms, and he dies from cardiac arrest while Maggie desperately searches for an alternative donor.
Also known as: Breast cancer
Maggie learns her breast cancer is not responding adequately to radiation therapy and will require additional hormone therapy. This ongoing battle affects her emotionally throughout the episode.
Also known as: Broken rib
Alice initially presents with rib fractures from the bus crash, which are diagnosed on X-ray and managed with pain medication before her respiratory condition worsens.
Also known as: Narcotic overdose
Val overdoses at the safe injection site and is successfully resuscitated with Narcan by Dr. Halstead and Dr. Choi.
Also known as: Heroin addiction
Mike's active heroin addiction has caused recurrent endocarditis and valve destruction. Dr. Halstead advocates for treating underlying depression to help him achieve sobriety, though Mike's girlfriend attempts to bring him drugs even in the hospital.