Also known as: Cancer of the esophagus
Harold O'Malley, George's father, undergoes a transhiatal esophagectomy despite widespread metastases. The surgery is the central focus of the episode, with complications discovered intraoperatively and family drama surrounding his prognosis.
Also known as: Leaking heart valve
Harold O'Malley had undergone aortic valve replacement prior to this episode as part of his treatment before the esophagectomy.
17-year-old with VATER syndrome (genetic condition affecting vertebra, anus, trachea, esophagus, and renal system) presenting for kidney stone removal and rib resection. Dr. Shepherd proposes radical spinal surgery involving vertebral resection and titanium cage placement, but insurance denial prevents the procedure.
Also known as: Kidney stones
Heather Douglas is scheduled for lithotripsy to remove kidney stones as part of her VATER syndrome complications.
Also known as: Intestinal obstruction in newborn
Four-day-old infant (Meredith's half-niece) with congenital intestinal blockage, previously corrected surgically. Develops life-threatening bowel perforation requiring emergency surgery when NG tube erodes through stomach wall.
Also known as: Nerve compression in arm
Preston Burke is post-op day one from incision and drainage of compressive hematoma affecting the brachial plexus. His hand function and potential tremors are a concern throughout the episode, though he refuses to discuss details with Cristina.