Also known as: Damaged heart valve
Eight-year-old Duncan is scheduled for a Ross procedure (pulmonary autograft) to replace his diseased aortic valve. The case drives significant plot as Duncan is terrified of surgery and pulls the fire alarm, requiring the surgical team to help him understand the procedure before he'll consent.
Also known as: Heart valve infection
The underlying cause of Duncan's aortic valve disease, mentioned as the reason he needs the valve replacement surgery.
Also known as: Brain tumor
Mr. Grandy presents with a massive tumor behind his eyes, described as baseball to grapefruit-sized. The tumor caused lethargy that his wife mistook for laziness during their European trip. Derek performs a bicoronal incision to remove it, and the case becomes contested between Izzie and Alex.
Also known as: TEN
Patient in the dermatology clinic who Cristina initially dismisses as having a simple rash. The patient crashes with 60% of her skin sloughing off, requiring emergency treatment with plasmapheresis and steroids. Initially misdiagnosed by Cristina as necrotizing fasciitis.