Also known as: Skin cancer that has spread
Izzie has recurrent brain metastases from melanoma discovered during the episode. A tiny tumor is found in her temporal lobe causing hallucinations of her deceased fiancé Denny. This is a continuation of her ongoing cancer arc and drives the emotional core of the episode as she gets married despite her prognosis.
Also known as: Heart bruising from trauma
College student driver in motor vehicle accident who develops multiple cardiac arrhythmias from blunt chest trauma, ultimately dying despite resuscitation efforts.
Also known as: Hole in the diaphragm
College valedictorian injured in the SUV crash with a large laceration in her diaphragm causing her stomach to herniate into her chest, requiring surgical repair.
Also known as: Fluid around the heart
College student in the crash who develops pericardial effusion from a chest wound, requiring emergency pericardiocentesis but ultimately dies despite intervention.
Also known as: Shock from blood loss
College student ejected from the vehicle in the crash who arrives at the hospital having lost massive amounts of blood, declared dead on arrival after prolonged attempts at resuscitation.
Also known as: Chest injury
College student in the crash with severe chest trauma and unstable blood pressure, requiring intensive resuscitation and monitoring.
Also known as: PTSD
Owen discusses his ongoing PTSD treatment with his psychiatrist, identifying that ceiling fan blades triggered a previous episode where he choked Cristina, mistaking them for helicopter blades from his combat experience.