TvDx
Grey's Anatomy

Grey's AnatomyABC

Season 5, Episode 23

5 medical diagnoses portrayed

Watch on Amazon

Also known as: GBM, terminal brain cancer

HallucinationsMemory impairmentSpeech impairmentPotential intracranial hemorrhage

Izzie must decide whether to undergo surgery to remove her hippocampus to excise the tumor, risking permanent memory and speech loss, or pursue IL-2 immunotherapy. After a Wada test shows severe impairment and she experiences worsening hallucinations, she ultimately chooses surgery and signs a DNR.

Grey's Anatomy — S05E23Patient: Izzie Stevens
Recurring storyline

Also known as: Chronic leg pain

Opioid dependenceFunctional impairment

A 19-year-old military lieutenant with intractable leg pain unresponsive to medications and physical therapy requests voluntary amputation so he can return to active duty in Iraq with a prosthetic. Despite concerns, Torres and Hunt ultimately perform the amputation.

Grey's Anatomy — S05E23Patient: Lieutenant Charlie Lowell

Also known as: Skin cancer that has spread

Bowel perforationCardiac arrestAnoxic brain injuryRespiratory failure

A 22-year-old patient with brain, liver, and kidney metastases who responded well to IL-2 immunotherapy for two years. During routine treatment, she develops a bowel perforation requiring emergency surgery, suffers cardiac arrest with resulting brain damage, and ends up on life support unable to breathe independently.

Grey's Anatomy — S05E23Patient: Alison Clark
Neuroblastomasupporting

Also known as: Spinal tumor

An 8-year-old patient undergoes successful surgery with Arizona Robbins, making a full recovery. This case is presented as a contrast to show 'the joy' of pediatric surgery when outcomes are positive.

Cholelithiasissupporting

Also known as: Gallstones

Bailey performs Seattle Grace's first single-incision gallbladder removal through the belly button using the new Da Vinci robotic surgical system, demonstrating the hospital's advancing surgical capabilities.