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Grey's Anatomy

Grey's AnatomyABC

Season 6, Episode 1

8 medical diagnoses portrayed

Watch on Amazon

Also known as: Head trauma

Elevated intracranial pressureBrain death

George O'Malley sustained a severe traumatic brain injury after being struck by a bus while saving someone's life. His intracranial pressure reached critical levels (ICP 30), and despite all interventions, he progressed to brain death and became an organ donor.

Grey's Anatomy — S06E01Patient: George O'Malley

Also known as: Propeller injuries

Hemorrhagic shockLower extremity amputation

Clara was involved in a speedboat accident where she was thrown from the boat and pulled into the propellers, resulting in bilateral arm amputations and severe lower extremity injury requiring leg amputation. She underwent multiple surgeries including limb reattachment attempts.

Grey's Anatomy — S06E01Patient: Clara Ferguson

Also known as: Shock from blood loss

Clara experienced severe blood loss from her traumatic injuries, with blood pressure dropping to the low 80s and requiring rapid transfusion and emergency surgical intervention.

Grey's Anatomy — S06E01Patient: Clara Ferguson
Scoliosissupporting

Also known as: Spinal curvature

A 15-year-old boy presented with chronic back pain, vomiting, and clumsiness. Initially diagnosed with mild scoliosis combined with growth spurts, but his worsening symptoms (fever, severe inguinal and leg pain) suggest a more serious underlying condition that remains undiagnosed by episode's end.

Also known as: Kidney failure

Cardiac arrest

Izzie experienced acute kidney failure following her cancer treatment, requiring intubation after coding. Her kidney function improved (BUN 15, creatinine 1.5) and she was eventually discharged from surgical care.

Grey's Anatomy — S06E01Patient: Izzie Stevens
Recurring storyline

Also known as: Skin cancer that has spread

Acute kidney injury

Izzie is recovering from metastatic melanoma treatment with IL-2 immunotherapy. She is discharged from surgical care but continues to be a cancer patient requiring ongoing rounds of IL-2 and PET scans.

Grey's Anatomy — S06E01Patient: Izzie Stevens
Recurring storyline

Also known as: Underdeveloped kidneys

An 8-year-old girl with hypoplastic kidneys who receives George O'Malley's donated kidneys during the organ recovery procedure.

Grey's Anatomy — S06E01Patient: Molly Kemper
Cystic fibrosissupporting

Also known as: CF

End-stage lung diseaseHeart failure

A 22-year-old patient with end-stage cystic fibrosis who receives George O'Malley's donated heart and lungs during the organ recovery procedure.

Grey's Anatomy — S06E01Patient: Terry Class