Also known as: Liver scarring
Thatcher presents with hematemesis and disorientation due to end-stage cirrhosis from chronic alcohol use. He requires an emergent liver transplant but is initially ineligible due to insufficient sobriety time. Meredith ultimately donates part of her liver.
Also known as: Liver scarring
The underlying chronic liver condition caused by alcoholism that leads to Thatcher's acute decompensation and need for transplant.
Also known as: Abdominal cancer
A 31-year-old patient with recurrent abdominal sarcoma presents with his third recurrence. Initial assessment deems the tumor inoperable due to extensive adhesions from prior surgeries. Izzie advocates for cytoreductive surgery with ball-tipped electrosurgery, though the patient ultimately dies during the procedure.
Also known as: ED
An 82-year-old man requests penile implant surgery (AMS 700) after failed medication trials. Despite family objections about his age, he is cleared medically and undergoes successful placement of a prosthetic device.
Also known as: Optic nerve tumor
Mentioned as a surgical case Derek is performing with Lexie, though not featured prominently in the episode.
Also known as: Metastatic skin cancer
Referenced as Izzie's ongoing condition as she returns to active surgical practice. Her personal experience with incurable cancer drives her advocacy for the sarcoma patient.