Also known as: Right-sided heart failure
Roy Henley, awaiting lung transplant, develops cor pulmonale (right-sided heart failure) due to chronic lung disease putting excess pressure on his heart. This leads to cardiogenic shock and requires an intraaortic balloon pump insertion and ECMO to keep him alive until transplant.
Also known as: Lung failure
Roy is on the transplant list for severe end-stage lung disease and receives new lungs during this episode. His lung failure had progressed to the point of causing secondary heart damage.
Also known as: Multiple organ failure
Mary Portman, age 30, died from multiple organ failure of unknown cause after a routine colostomy reversal. Bailey performs an autopsy throughout the episode trying to determine the cause of death, which remains inconclusive.
Also known as: Major injuries from car accident
A simulated mass casualty scenario for trauma certification involving approximately 30 victims from a charter plane collision with a Greyhound bus. Multiple blunt trauma injuries are treated as part of the training exercise.
Also known as: PTSD
Cristina continues to struggle with PTSD from the hospital shooting, experiencing persistent fear and anxiety. She has a breakdown when discussing how she was forced to operate on Derek under gunpoint, revealing she feels 'ruined' and 'dead inside.'
Also known as: Early-onset Alzheimer's
Derek is working on a grant proposal for Alzheimer's research and clinical trial, motivated by fears about Meredith potentially developing early-onset Alzheimer's like her mother Ellis Grey. This creates tension between Derek and Meredith.