Season 8, Episode 5

Also known as: Penis cancer

Ryan underwent a full penectomy due to penile cancer and is now receiving the country's first penis transplant to restore urinary and sexual function. This serves as the central teaching case of the episode.

Also known as: Blocked intestine

Zola presents with fever, abdominal distention, and seizures due to a bowel obstruction compressing her VP shunt. The case creates significant emotional conflict as Meredith and Derek are prohibited from treating her due to the suspended adoption.

Also known as: Water on the brain

Zola's pre-existing hydrocephalus is managed with a VP shunt that becomes kinked due to the bowel obstruction, requiring surgical correction during her emergency surgery.