Also known as: Brain tumor
A father presents with inappropriate sexual behavior (grabbing people) which is discovered to be caused by a frontal lobe tumor. The tumor causes disinhibition and return of primitive reflexes like grasping. Initially deemed inoperable, Derek Shepherd is consulted to perform the complex surgery.
Also known as: Liver scarring
A 65-year-old patient with cirrhosis progressing to end-stage liver disease over seven years. He undergoes simultaneous heart valve replacement and liver transplant surgery, but his body rejects the new liver. Given only a week to live after rejection.
Also known as: Heart valve damage
Same patient with end-stage liver disease also developed valvular heart disease requiring valve replacement surgery with a pericardial bioprosthesis before the liver transplant could be performed.
Also known as: Kidney injury from bus accident
A 14-year-old boy dragged 20 yards by a horse after his foot slipped through the stirrup due to wearing improper footwear. Presents with abdominal tenderness and bleeding requiring exploratory laparoscopy on Arizona's first day back.
Also known as: Kidney tumor
A 6-year-old pediatric patient mentioned as part of Arizona Robbins' surgical schedule on her first day back to work.
Also known as: Nerve damage
Derek's ongoing hand injury from the plane crash continues to be a central storyline. Multiple surgical approaches are being researched including nerve transfers, cable grafts, and end-to-side transfers to restore hand function. Derek struggles with whether to proceed with surgery.
Also known as: Leg amputation
Arizona's first day back at work after her plane crash amputation. She struggles physically and emotionally, ultimately falling when she puts weight on her prosthetic leg. The episode focuses on her adjustment to the disability.