Also known as: Descending infection from dental procedure
Holly develops a severe infection spreading from a root canal procedure into her neck and mediastinum (chest cavity around the heart and lungs), causing sepsis and requiring emergency surgery. The infection is so aggressive it closes her airway and requires an emergency cricothyroidotomy.
Also known as: Brain infection
Holly develops a brain abscess from the dental infection that is positioned dangerously against her brain ventricle. This creates a surgical dilemma about whether to address the chest infection or brain infection first, with Derek advocating for brain surgery and Maggie advocating for chest surgery.
Also known as: Blood infection
Holly develops sepsis from the spreading infection, which fails to respond to IV antibiotics and drives the urgency for surgical intervention.
Also known as: Head trauma
Jordan, a veteran learning to use a robotic leg, falls down stairs during training and suffers a severe traumatic brain injury with multifocal hemorrhage. He requires a full craniotomy and falls into a coma with uncertain prognosis.
Also known as: Brain tumor
Arizona discovers that Dr. Herman has a large, inoperable astrocytoma (brain tumor) described as extending from the subfrontal region into the hypothalamus. Herman has been told she has only 5 months to live. Amelia later reviews the scans and believes she may be able to remove it.
Also known as: Brittle bone disease
Edwards identifies potential signs of osteogenesis imperfecta type II or III in April and Jackson's unborn baby during an ultrasound, including short femurs, abnormal head mineralization, and no fetal movement. Herman confirms this is likely a fatal condition where the baby would have a very short, painful life.