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Grey's Anatomy

Grey's AnatomyABC

Season 12, Episode 3

5 medical diagnoses portrayed

Watch on Amazon

Also known as: Liver cancer

Acute kidney injuryHeart failureRespiratory distress

Newborn twins are both born with aggressive liver tumors causing multi-organ failure. The episode centers on Karev's difficult decision about which twin receives the only available liver transplant, ultimately choosing Emma while attempting a tumor resection on Daniel, who dies during surgery.

Grey's Anatomy — S12E03Patient: Emma and Daniel (newborn twins)

Also known as: Kidney failure

Both newborn twins develop renal failure as a complication of their liver tumors invading their kidneys, contributing to their critical condition and need for urgent transplant.

Grey's Anatomy — S12E03Patient: Emma and Daniel

Also known as: Newborn jaundice

Both twins present with jaundice at birth, which is the initial sign that leads to discovery of their liver tumors.

Grey's Anatomy — S12E03Patient: Emma and Daniel

Also known as: RDS, immature lungs

Both twins experience respiratory distress at birth due to their tumors affecting lung function, requiring immediate NICU care with ventilator support.

Grey's Anatomy — S12E03Patient: Emma and Daniel
Constipationsupporting

A pediatric patient being treated by Karev for constipation, kept in the hospital until she can have a bowel movement. This is a minor case that provides comic relief and shows Karev's peds work.