Also known as: AVM
Frankie suffers a bleeding AVM during medevac transport when heparin anticoagulation worsens the hemorrhage. He requires emergency surgery to stop the bleeding and prevent further neurological damage.
Also known as: Shock from blood loss
Claude experiences massive blood loss during surgery while blood bank access is locked due to cyberattack. Surgeons donate their own blood directly while controlling multiple bleeding sites during a distal pancreatectomy.
Post-tracheostomy patient develops life-threatening bleeding from a fistula between his trachea and innominate artery. Kepner saves him by manually compressing the vessel through the trach site while intubating.
Also known as: Blood clotting disorder
Female surgical patient burns through all clotting factors during surgery, requiring FFP and multiple ligations to control bleeding from multiple sites during the cyberattack crisis.
Also known as: Intimate partner violence
Jo's history of severe domestic violence by her ex-husband Paul is revealed, including multiple beatings resulting in broken ribs, eye injuries, and near organ rupture. This drives the episode's central emotional arc when Paul arrives at the hospital.
Also known as: Hit-and-run injuries
Paul Stadler is struck by a vehicle in a hit-and-run at the episode's end, arriving as a trauma patient with intact ABCs but hypertensive and tachycardic, requiring immediate assessment.