Also known as: Bile duct blockage
Flor requires a Roux-en-Y hepaticojejunostomy to remove a choledochal cyst in her biliary system that poses a risk of developing cancerous cells. The surgery is successful and becomes emotionally significant as her family celebrates Day of the Dead.
Also known as: Copper accumulation disorder
Roberta is a 45-year-old woman with Wilson's disease awaiting her fourth liver transplant. After multiple failed attempts, Bailey performs an innovative procedure using normothermic perfusion to revive a liver from a cardiac death donor, successfully transplanting it into Roberta.
Also known as: Bone cancer
A young boy presents with a humerus fracture from climbing a fence. Imaging reveals a mass causing pathologic fracture, diagnosed as telangiectatic osteosarcoma. Link, who survived the same cancer as a child, counsels the frightened mother and patient.
Also known as: Broken arm
J.J.'s humerus fracture is the presenting injury that leads to discovery of his underlying osteosarcoma. The fracture occurred because the tumor weakened the bone.
Also known as: Blood cancer
Meredith learns from Richard that her estranged father Thatcher is dying of acute myeloid leukemia and is in hospice with only weeks to live. This drives Meredith's emotional arc throughout the episode as she grapples with whether to say goodbye.
Also known as: Blood clot in lung
Ned, a patient who had bowel resection the day before, codes and dies after throwing a clot. His death provides the opportunity for Bailey to attempt the innovative normothermic liver perfusion procedure, as he was an organ donor and blood match for Roberta.