Also known as: C-section scar pregnancy
Susan is a 39-year-old patient with a cesarean scar ectopic pregnancy who seeks care across state lines from Idaho. The pregnancy ruptures during transport, causing massive hemorrhage and ultimately her death despite Bailey and Addison's attempts to save her. This case drives the episode's central conflict about abortion restrictions preventing timely medical care.
Also known as: Brain bleed
Amelia mentions having an epidural hematoma patient as an emergency, which she uses to justify asking Lucas to take Scout to daycare. The case is referenced but not shown in detail.
Also known as: Panic attacks
Zola is experiencing frequent panic attacks characterized by dizziness, shaking, and breathing difficulties. Her anxiety stems from fear of Alzheimer's disease affecting her family. This condition is central to Meredith's storyline and her decision-making about moving to Boston and taking on Alzheimer's research.
Also known as: Spinal cancer
Catherine's spinal tumor has grown by two millimeters, indicating disease progression rather than remission. She refuses further chemotherapy treatment, opting instead for alternative medicine approaches. Tom Koracick reveals she has been hiding this progression from her family. This drives a significant subplot about her autonomy and end-of-life choices.