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Grey's Anatomy

Grey's AnatomyABC

Season 21, Episode 2

8 medical diagnoses portrayed

Watch on Amazon

Also known as: Esophageal tear

Aorto-esophageal fistulaGastrointestinal hemorrhageInfection

Nora has a perforated esophagus from a previous Nissen fundoplication surgery that was repaired but continues to leak. During treatment, she develops a life-threatening aorto-esophageal fistula causing massive bleeding that requires emergency balloon tamponade and stent placement.

Grey's Anatomy — S21E02Patient: Nora Young
Gastrointestinal hemorrhageHemorrhagic shock

Nora develops a fistula between her aorta and esophagus, causing massive hemorrhage requiring emergency Minnesota tube placement and TEVAR with stent placement to control bleeding.

Grey's Anatomy — S21E02Patient: Nora Young

Also known as: Blood clot in liver vein

Hepatic lesions

Catherine is being treated for Budd-Chiari syndrome and develops concerning liver lesions on imaging that are suspected to be either metastatic cancer or new primary cancer, though Bailey and Meredith propose they could be benign findings related to her vascular condition.

Grey's Anatomy — S21E02Patient: Catherine Fox
Recurring storyline

Also known as: LFS

Adrenocortical carcinomaDiffuse intrinsic pontine glioma

Cal has Li-Fraumeni syndrome, a genetic disorder causing predisposition to multiple cancers. He is in remission from adrenocortical carcinoma but presents with back pain, which is discovered to be from a benign schwannoma and a separate, ultimately fatal brain tumor.

Grey's Anatomy — S21E02Patient: Cal Huang
Spinal cord compression

Cal has a large benign schwannoma of the thoracic nerve root that has invaded the spinal column and is compressing the spinal cord, causing significant back pain. It requires complex surgical resection via simultaneous anterior and posterior approach.

Grey's Anatomy — S21E02Patient: Cal Huang

Also known as: DIPG

During post-operative seizure workup, Cal is diagnosed with a rapidly-growing malignant brain tumor in the pons with satellite lesions. This is a terminal diagnosis with weeks to months prognosis, devastating for a 15-year-old patient.

Grey's Anatomy — S21E02Patient: Cal Huang

Cal was previously treated for adrenocortical carcinoma two years ago and is currently in remission from this cancer, though it is part of his Li-Fraumeni syndrome presentation.

Grey's Anatomy — S21E02Patient: Cal Huang
Amnesiasupporting

Also known as: Memory loss

A woman with amnesia from a previous car accident has no memory of her relationship with Kwan, requiring him to explain their past engagement and breakup.

Grey's Anatomy — S21E02Patient: Character in Kwan's storyline
Recurring storyline