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Grey's Anatomy

Grey's AnatomyABC

Season 21, Episode 5

7 medical diagnoses portrayed

Watch on Amazon

Also known as: Flesh-eating lung infection

Complete lung liquefactionAntibiotic-resistant infectionRespiratory failure requiring ECMO

High school band director with rapidly progressing necrotizing pneumonia requiring VV ECMO support. His entire left lung is liquified from necrotic tissue, necessitating a pneumonectomy while awaiting lung transplant.

Grey's Anatomy — S21E05Patient: Darren Riley

Also known as: Fluid around the heart

Cardiac tamponadeHemodynamic collapse

Post-cardiac surgery patient who develops a pericardial effusion that progresses to cardiac tamponade. Owen performs emergency bedside drainage when the patient crashes, with dramatic blood spray witnessed by the patient's wife.

Grey's Anatomy — S21E05Patient: Aurelio Wheeler

Also known as: Sickle cell

Avascular necrosis of hipNonfunctional spleenLiver iron depositsCholelithiasis

Hospital custodial staff member with severe sickle cell disease causing avascular necrosis requiring hip replacement. The episode explores his inability to afford the $3 million gene therapy cure despite working at a hospital, ultimately receiving a grant to potentially access the treatment.

Grey's Anatomy — S21E05Patient: Zayne Johnson

Also known as: Head trauma

Subdural hematomaMultiple contusions and lacerations

10-year-old girl who fell off a moving tractor, sustaining head trauma with subdural bleeding. Transported by helicopter during a storm, requiring close neuro monitoring.

Grey's Anatomy — S21E05Patient: Ofelia Lopez

Also known as: Severe leg injury

Superficial femoral artery injuryExtensive soft tissue damageProlonged ischemia

Severe left leg trauma from tractor accident with vascular injury requiring emergency tourniquet. During helicopter transport, Schmitt and Adams improvise a temporary arterial shunt using IV tubing to save the limb when the tourniquet breaks.

Grey's Anatomy — S21E05Patient: Ofelia Lopez

Also known as: Insecticide poisoning

Seizure disorderBradycardiaExcessive secretions

Farm accident patient develops signs of organophosphate toxicity during helicopter transport (pinpoint pupils, bradycardia, diaphoresis, seizure), requiring atropine treatment. Likely from pesticide exposure while playing in fields.

Grey's Anatomy — S21E05Patient: Ofelia Lopez

Also known as: Twins

Jo is pregnant with twins and experiencing anxiety about the high-risk nature of the pregnancy. She and Link struggle with communication and fear about managing twin newborns while both working as surgeons.

Grey's Anatomy — S21E05Patient: Jo Wilson
Recurring storyline