Also known as: Third-degree burn
Adam sustains 40% body surface burns from an ATV crash with gasoline fire. The extensive burns complicate all diagnostic testing and drive the episode's medical mystery as the team must find alternative ways to diagnose underlying conditions without standard imaging or invasive procedures.
Also known as: Too much serotonin from medication overdose
The ultimate diagnosis causing Adam's seizures, abnormal heart rhythm, and neurological symptoms. Caused by over-the-counter smoking cessation medication containing antidepressants that Adam was secretly taking, leading to excessive serotonin and life-threatening complications.
Also known as: Seizure
Adam experiences multiple seizures - one causing the initial ATV crash (indicated by him blacking out and urinating), and another during the galvanometer test. The seizures are ultimately determined to be caused by serotonin syndrome from smoking cessation medication.
Also known as: Ruptured aneurysm
Discovered via transcranial Doppler sonography during workup. The team surgically repairs the bleed in the subarachnoid space, though this is not the primary cause of Adam's neurological symptoms.
Also known as: Rapid heart rate
Adam presents with abnormal heart rhythm that cannot be fully explained by the burn injury alone. The tachycardia is part of the constellation of symptoms from serotonin syndrome.
Also known as: Migraine headache
House deliberately induces a migraine in himself by taking Dr. Weber's experimental migraine prevention medication to prove it doesn't work. He experiences severe migraine with visual hallucinations (synesthesia - seeing music) and takes LSD and antidepressants to counter the symptoms.