TvDx
House

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Season 2, Episode 23

3 medical diagnoses portrayed

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Also known as: SVT

Cardiogenic shockCardiac arrest during electrophysiology study

Initial presentation with cardiogenic shock and arrhythmia detected during electrophysiology study. The team performs cryoablation near the coronary sinus to eliminate the abnormal electrical pathway, but subsequent hallucinations reveal this was not the primary problem.

House — S02E23Patient: Leona

Also known as: Iron overload

Liver failureGastrointestinal bleedingReverse peristalsisSkin hyperpigmentation

Hereditary hemochromatosis causing progressive liver failure and neurological symptoms including hallucinations triggered by pain. House diagnoses this by analyzing her deceased grandfather Jesse Baker's music recordings, noting personality changes and altered aural perception that suggest iron overload rather than substance abuse.

House — S02E23Patient: Leona

Also known as: Mucormycosis

Pulmonary infiltratesRespiratory failureLung tissue destruction

Life-threatening fungal infection contracted from living in a mold-contaminated recording studio after Hurricane Katrina. The fungus bound with excess iron mobilized by deferoxamine treatment, causing acute lung destruction. House determines the location of exposure by recognizing Leona lied about living at a shelter, using the sound-proofed, moisture-damaged studio as the source of severe mold exposure.

House — S02E23Patient: Leona