Also known as: EPP
A six-year-old girl presents with pancreatitis, gallstones, and progressive symptoms including rash and liver dysfunction. The team eventually discovers she has a genetic disorder causing her blood cells to produce chemicals in reaction to light, which damage her liver and create gallstones. Her worsening under surgical lights is the key diagnostic clue.
Alice's initial presentation after an amusement park ride. The pancreatitis is later revealed to be a complication of her underlying erythropoietic protoporphyria.
Also known as: Gallstones
Unusual gallstones in a six-year-old patient that lead the team through multiple diagnostic theories. The gallstones are eventually identified as a byproduct of her erythropoietic protoporphyria, created when the liver filters damaged blood cells.
Also known as: Heroin addiction
House's Vicodin addiction and Detective Tritter's investigation create a major subplot. His withdrawal symptoms affect his behavior toward the team, and Cuddy takes control of his prescriptions while Tritter pressures the staff to testify against him.