Also known as: Extra coronary artery opening
Marina has a third coronary ostium (opening), a never-before-seen congenital heart defect that causes inflammation, throws off blood clots, and ultimately caused her cardiac arrest during angiogram. House diagnoses this after she miraculously recovers from hours of cardiac arrest on bypass, attributing her cardiac arrest to 'God's error' rather than human error.
Also known as: Heart stopped
Marina's heart stops during a routine cardiac catheterization, remaining stopped for over three hours despite CPR and bypass support. The team debates whether it was human error or an underlying condition. She miraculously recovers after the husband prays, with her heart spontaneously restarting.
Also known as: MS
Foreman initially diagnoses MS based on pain, fatigue, double vision, and kidney problems visible on MRI. Treatment with Interferon is initiated but proves incorrect when her pain worsens and she develops pathological fracture, leading to a revised diagnosis.
Also known as: Broken arm from weak bones
During examination, Foreman inadvertently breaks Marina's arm with minimal pressure, revealing severe bone fragility. This leads the team to suspect bone cancer, though PET scan rules this out. The fracture is ultimately attributed to her underlying systemic condition.
Also known as: Kidney failure
Marina presents with bloody urine and kidney dysfunction, initially attributed to severe dehydration from being lost at sea for three days. However, her husband has similar symptoms, complicating the differential diagnosis.