
Also known as: Tonic water allergy
The central mystery of the episode involves soap opera actor Evan Greer presenting with progressive symptoms including peripheral vision loss, foot numbness, cardiac arrest, kidney failure, and coma. House ultimately diagnoses a severe allergic reaction to quinine from tonic water in gin and tonics that the character Brock Sterling drinks on the show, which the actor had been consuming for two months.
Also known as: Kidney failure
The patient develops acute kidney failure revealed during iodine uptake testing, requiring dialysis. This kidney dysfunction is ultimately attributed to the systemic effects of the quinine allergy.
Also known as: Heart stopped
During diagnostic testing in the sleep lab, the patient's heart rate climbs to 220 and he goes into cardiac arrest, requiring electrical cardioversion to restore normal rhythm. This is part of the severe systemic allergic reaction.