TvDx
House

HouseFox

Season 5, Episode 3

7 medical diagnoses portrayed

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Also known as: Inability to recognize visual objects or people

Intermittent episodes

A struggling artist presents with acute onset visual agnosia after painting a distorted portrait. The symptom appears intermittently throughout the episode, initially thought to be neurological but ultimately caused by drug interactions.

House — S05E03Patient: Brandon

Also known as: Seizure

Brandon experiences a sudden seizure after initially being told he was recovering, prompting the team to realize the experimental drugs were still affecting him.

House — S05E03Patient: Brandon
Angioedemasupporting

Also known as: Throat swelling

Airway obstruction requiring emergency tracheostomyTear duct compression

Brandon develops massive facial and neck swelling that closes his throat, requiring an emergency tracheostomy. His face swells so severely it compresses his tear ducts.

House — S05E03Patient: Brandon

Also known as: Irregular heartbeat

Ventricular tachycardiaRisk of sudden cardiac death

Brandon develops dangerous heart rhythm abnormalities during testing, with ventricular tachycardia requiring cardioversion. Initially suspected to be Romano-Ward Syndrome.

House — S05E03Patient: Brandon
Hypersexualitysupporting

Also known as: Excessive sexual arousal

Brandon develops inappropriate hypersexuality as one of his symptoms, initially leading the team to consider Klüver-Bucy Syndrome.

House — S05E03Patient: Brandon
Bezoarmajor

Also known as: Foreign matter blockage in digestive tract

Drug sequestration and intermittent release

The final diagnosis: a bezoar formed from undigested food due to low stomach acid from an experimental antacid. The bezoar trapped and intermittently released experimental drugs, causing all his symptoms through drug interactions.

House — S05E03Patient: Brandon

Also known as: Drug poisoning

Multiple organ system effectsDrug interactions

Brandon participated in three simultaneous clinical trials for experimental drugs (anticoagulant, autoimmune treatment, and anticonvulsant). The interactions between these untested drugs, stored in a bezoar and intermittently released, caused all his presenting symptoms.

House — S05E03Patient: Brandon