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House

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Season 5, Episode 5

8 medical diagnoses portrayed

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Lung cystsRenal tubular acidosisCandidiasis

The central mystery of the episode. A woman presents with seizure, retinal vein occlusion, cardiac arrest, kidney problems, and lung cysts. Eventually diagnosed as Sjögren's syndrome causing multiple systemic complications including lack of tear/saliva production, lung cysts, and renal tubular acidosis.

House — S05E05Patient: Spencer

Also known as: Seizure

Initial presenting symptom that brings the patient to the hospital. Initially attributed to dehydration and drug use but ultimately part of the broader Sjögren's syndrome presentation.

House — S05E05Patient: Spencer
Cardiac arrestsupporting

Also known as: Heart stopped

The patient experiences cardiac arrest requiring defibrillation. This symptom escalates the case from a simple seizure to a multi-system problem.

House — S05E05Patient: Spencer

Also known as: RTA

HypokalemiaKidney calcifications

Incorrectly diagnosed as the primary condition causing kidney calcifications and low potassium. Patient undergoes surgery to remove calcifications before the team realizes this is a complication of Sjögren's syndrome.

House — S05E05Patient: Spencer
Pneumothoraxsupporting

Also known as: Collapsed lung

A lung cyst ruptures during the methacholine challenge test, causing lung collapse. Thirteen recognizes the problem and re-inflates the lung.

House — S05E05Patient: Spencer
Candidiasissupporting

Also known as: Fungal infection

Opportunistic fungal infection in the mouth caused by lack of saliva from Sjögren's syndrome. This same infection affects Thirteen due to her asthma inhaler use, providing a diagnostic clue.

House — S05E05Patient: Spencer

Also known as: Huntington's disease

Thirteen's ongoing terminal diagnosis drives her destructive behavior throughout the episode including drug use, promiscuous sex, and self-destructive choices. Foreman confronts her about her CAG test results showing she has less time than expected.

House — S05E05Patient: Dr. Remy 'Thirteen' Hadley
Recurring storyline
Asthmasupporting
Candidiasis

Thirteen's childhood asthma has returned since moving to a new apartment. Her inhaler use causes the same fungal mouth infection as the patient, providing the key diagnostic clue.

House — S05E05Patient: Dr. Remy 'Thirteen' Hadley