TvDx
House

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Season 5, Episode 8

4 medical diagnoses portrayed

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Also known as: APL

Brain lesionsNeed for bone marrow transplant

16-year-old emancipated minor presents with pulmonary edema and delirium. Through multiple misdiagnoses, the team discovers she has acute promyelocytic leukemia. The arsenic in pressure-treated wood furniture she was exposed to was inadvertently slowing the leukemia progression. Once chelated of arsenic, brain lesions rapidly develop. She requires bone marrow transplant but must confront estranged parents for best donor match.

House — S05E08Patient: Sophia (actually using false identity)
Iron poisoningsupporting

Also known as: Vitamin overdose with iron

Cardiac arrestGastrointestinal bleedingAltered mental status

4-year-old boy presents with bloody vomit, diarrhea, lethargy, and uncontrollable giggling, eventually suffering cardiac arrest. Foreman discovers the older brother has been giving him extra children's vitamins trying to make him stronger, causing iron toxicity.

House — S05E08Patient: Jonah

Also known as: Arsenic poisoning

Pulmonary edemaHemolysis

Patient was exposed to arsenic from sawing or working with pressure-treated wood furniture. This exposure caused brown urine from hemolysis but was paradoxically treating her underlying leukemia. Once chelated, her condition worsened as the arsenic had been suppressing the APL.

House — S05E08Patient: Sophia

Also known as: Huntington's disease

Thirteen reveals her Huntington's disease diagnosis to the patient Sophia in an attempt to convince her to accept life-saving treatment. She uses her own terminal diagnosis to emphasize the importance of living as long as possible.

House — S05E08Patient: Thirteen
Recurring storyline