Also known as: Sleep disorder
House has not had REM sleep for four nights, leading to visual and auditory hallucinations of Amber (Wilson's dead girlfriend). This insomnia drives much of his erratic behavior throughout the episode and is revealed to have started after Kutner's suicide.
Initial presenting symptom: a deaf 14-year-old wrestler started hearing imaginary explosions. Quickly ruled out as the diagnosis.
Also known as: Profound hearing loss
Patient has been deaf since age 4, originally attributed to meningitis complications. House controversially installs a cochlear implant without consent during surgery, which the patient later rips out. The deafness becomes a central ethical conflict in the episode.
Also known as: Vision loss from immune response
Patient suddenly loses vision in one eye during seizure lab testing. House's hallucination correctly predicts this based on elevated C-reactive protein levels.
Also known as: Nerve damage, numbness
Patient develops numbness and decreased sensation in his hands, affecting his wrestling performance and causing balance issues.
Also known as: Abnormal EKG
Patient develops arrhythmia discovered when he tears out his cochlear implant. This leads the team toward the correct diagnosis by revealing systemic involvement.
Also known as: Excessive urination
Patient experiences sudden severe urinary incontinence, urinating liters at night. This symptom helps point toward the systemic nature of his condition.
Also known as: Sarcoid
Final diagnosis: patient has dormant sarcoidosis that was suppressed by tobacco toxins from chewing tobacco for weight cutting. When he quit chewing, the absence of toxins kicked the condition into hyperdrive, causing all his symptoms including lung failure requiring ventilation.
Also known as: Severe allergic reaction
Chase goes into anaphylactic shock at his bachelor party from contact with strawberry-containing body butter, requiring EpiPen treatment. House may have subconsciously orchestrated this, knowing about Chase's strawberry allergy.