TvDx
House

HouseFox

Season 5, Episode 23

8 medical diagnoses portrayed

Watch on Amazon

Also known as: TEN

Skin sloughingRisk of sepsisBlood loss risk

Ballet dancer develops life-threatening skin sloughing (toxic epidermal necrolysis) as a severe reaction to antibiotics prescribed by House, losing 80% of her skin and requiring artificial skin grafts.

House — S05E23Patient: Penelope

Also known as: Gonorrhea with joint infection

Cardiac abscessSepsisGangrene of extremities

The primary diagnosis: gonorrhea disseminated to form an abscess on the patient's heart, causing respiratory collapse and requiring cardiac surgery. Post-surgical complications from vasoconstrictors led to gangrene requiring amputation of hands and feet.

House — S05E23Patient: Penelope

Also known as: Infection pocket in the heart

Atrial fibrillationRespiratory failureSepsis

Walled-off infection on the patient's heart that appeared as a shadow on MRI, caused her lungs to collapse and required stopping her heart to properly image and then surgical removal.

House — S05E23Patient: Penelope

Also known as: A-fib

Risk of cardiac arrest

Patient develops dangerous irregular heart rhythm during liver biopsy procedure that complicates diagnosis and requires stopping her heart to get proper imaging.

House — S05E23Patient: Penelope

Also known as: Tissue death

Required amputation of hands and feet

Dopamine used during cardiac surgery caused extreme vasoconstriction, cutting off blood flow to the patient's extremities and causing tissue death requiring amputation of both hands and feet.

House — S05E23Patient: Penelope

Also known as: Seeing things that aren't there

Inability to practice medicineRisk to patients

House experiences persistent visual hallucinations of Amber (Wilson's dead girlfriend) and Kutner throughout the episode, representing his psychological breakdown and leading him to consider he may have MS, schizophrenia, or Vicodin toxicity. This is the central character arc driving the episode.

House — S05E23Patient: House
Recurring storyline

Also known as: Heroin addiction

HallucinationsImpaired judgmentRisk to patients

House's long-term Vicodin addiction is revealed as the cause of his hallucinations. He undergoes withdrawal at the end of the episode with Cuddy's help, marking a major turning point in his character arc.

House — S05E23Patient: House
Recurring storyline

Also known as: Kidney cancer

Brief scene where House diagnoses a patient with kidney cancer before being interrupted by Cuddy regarding his hallucinations.

House — S05E23Patient: Mr. Pietramala