Also known as: Opioid addiction
House is admitted to Mayfield Psychiatric Hospital after experiencing hallucinations related to years of Vicodin abuse. His recovery from opioid dependence is the central storyline of this episode.
Also known as: Depression
Dr. Nolan diagnoses House with underlying depression triggered by the deaths of colleagues and his father, which goes deeper than his substance abuse. This becomes a primary focus of House's psychiatric treatment throughout the episode.
Also known as: Manic depression
Alvie is House's roommate who has bipolar disorder and stopped taking his medications because he believes nothing is wrong with him. He eventually decides to resume treatment at the end of the episode.
Also known as: Shared delusion
Steve believes he is a superhero called Freedom Master with special powers. House challenges this delusion by having him attempt to save another patient, which results in severe injury and catatonic state after his delusion is shattered.
Also known as: Ruptured spleen
Freedom Master sustains a lacerated spleen along with multiple other traumatic injuries when he jumps off a building attempting to save Silent Girl, resulting from House's manipulation of his delusions.
Also known as: Broken pelvis
Part of the multiple traumatic injuries sustained by Freedom Master when he jumps from a building.
Also known as: Broken thigh bone
Compound fracture of the femur sustained during Freedom Master's fall from the building.
Also known as: Broken arm
Compound fracture of the humerus sustained during Freedom Master's traumatic fall.
Also known as: Selective mutism
Annie has not spoken for over a decade after her husband's death on 9/11. She eventually speaks again and is discharged to a rehabilitation facility, representing a therapeutic success story that contrasts with Freedom Master's outcome.
Also known as: Bleeding in the brain
Dr. Nolan's father suffers a lacunar infarct that converts to a hemorrhagic stroke, resulting in catastrophic brain injury. Nolan asks House for a consultation, which becomes a pivotal moment in their therapeutic relationship.
Also known as: Severe eating disorder
A male patient on the ward who has anorexia and expresses concern about gaining weight despite eating less, which House cruelly mocks during group therapy.
Also known as: Suicide attempt
A patient on the ward who previously attempted suicide by cutting her wrists, which House insensitively brings up during his first group therapy session.
Jay repeatedly asks to go outside during group therapy sessions, and House identifies him as claustrophobic, using this information to mock and manipulate other patients.