TvDx
House

HouseFox

Season 8, Episode 14

5 medical diagnoses portrayed

Watch on Amazon

Also known as: Fungal brain infection

Pulmonary infectionOrbital necrotizing infection with tissue lossCerebral venous sinus thrombosisDrug-induced deafness from treatment

A blind diabetic accountant presents with disorientation, hallucinations, seizures, and tooth loss. Initially misdiagnosed as periodontitis and then Behcet's syndrome, the team ultimately discovers a rapidly spreading fungal infection (mucormycosis) that attacked his lungs and eyes. Treatment with amphotericin B saves his life but causes permanent hearing loss.

House — S08E14Patient: Will

Also known as: Blood clot in the brain

Pulmonary embolismRisk of cerebral edema

A large clot discovered in the patient's brain that explained his initial disorientation, hallucinations, and seizures. Treatment with heparin caused a piece to break off and travel to his lungs. Ultimately determined to be secondary to the underlying mucormycosis infection.

House — S08E14Patient: Will

Also known as: Diabetes

Compromised immune system making him susceptible to mucormycosisPeriodontitis

Pre-existing condition in the patient that compromised his immune system, making him particularly vulnerable to the aggressive fungal infection and contributing to his periodontal disease.

House — S08E14Patient: Will
Periodontitissupporting

Also known as: Gum disease

Tooth loss (three teeth detached from jaw)

Initially thought to be the primary diagnosis when the patient's teeth detached and lodged in his throat. The team treated it as a bacterial infection that progressed systemically, but this was a red herring - the severe presentation was actually due to the underlying mucormycosis.

House — S08E14Patient: Will

Also known as: Drug-induced deafness

Permanent hearing loss

The high dose of amphotericin B required to treat the patient's mucormycosis causes permanent hearing loss, presenting the patient with the difficult choice of dying from the infection or living blind and deaf.

House — S08E14Patient: Will