
Also known as: Terminal cancer
Max is facing treatment decisions for his cancer. He opts for precision-targeted immunotherapy over traditional chemo/radiation despite risks, seeking enrollment in a clinical trial led by Dr. Panthaki. By episode's end, he's accepted into the trial.
Also known as: Clotting factor deficiency
Sarah presents with severe spontaneous bleeding due to acquired hemophilia (factor VIII deficiency). Treatment requires precise continuous factor replacement infusion, monitored by frequent PTT testing. She must pass three consecutive normal PTT tests to qualify for heart transplant.
Also known as: Heart transplant rejection
Sarah's transplanted heart (received 27 years ago from Max's sister Luna) shows Grade 4 rejection on biopsy with fibrosis and T-lymphocyte infiltration. Low cyclosporin levels indicated inadequate immunosuppression. The heart is failing and she requires a new transplant.
Also known as: Stomach pain
Patient presents with new onset right-sided abdominal pain, treated conservatively with antibiotics. Used to demonstrate Dr. Bloom's medical errors due to exhaustion when she nearly orders wrong antibiotic (patient allergic to Cephilicam).
Also known as: Transgender
Transgender teen seeking medical clearance for top surgery (gender confirmation surgery). Evaluated and cleared medically but advised to wait one year to assess effects of hormone blockers on breast tissue before determining appropriate surgical approach.
Also known as: Exhaustion
Dr. Bloom is shown making increasing medical errors due to exhaustion, including nearly prescribing an antibiotic to an allergic patient and leaving gaps in documentation. Confronted by Dr. Reynolds about needing help.