
Also known as: Pancreatic tumor
Mr. Azad had pancreatic cancer surgically resected but now requires a second surgery to clear positive margins. The case becomes central to the episode's plot about hospital billing practices when he receives a massive bill and initially refuses the life-saving follow-up surgery.
Also known as: Brain attack
Helen is recovering from a stroke with significant aphasia affecting her speech and language abilities. She struggles with word-finding and articulation throughout the episode, attending intensive speech therapy sessions. This is a major ongoing character arc affecting her relationship with Max.
Also known as: Gluten intolerance
Kyle presents with symptoms initially attributed to MS including numbness, weakness, and rashes. He had been misdiagnosed and underwent an inappropriate fecal transplant. Lauren and Mia discover his symptoms are actually caused by celiac disease, with gluten from his own calzones triggering severe immune inflammation.
Also known as: MS
Kyle was misdiagnosed with MS and underwent an unindicated fecal microbiota transplant for supposed MS symptoms. He later developed complications from the inappropriate treatment before the correct diagnosis of celiac disease was made.
Also known as: Severe allergic reaction
Kyle develops anaphylactic shock as a reaction to broad-spectrum antibiotics given to reverse his fecal transplant complications. He becomes tachycardic, hypotensive, and requires emergent epinephrine treatment.
Also known as: Callous-unemotional traits
Juliet, a patient with documented callous-unemotional traits, acts out violently after a breakup and later seeks revenge. The episode explores her difficulty connecting emotionally with others, though she shows progress when she experiences genuine grief and tears over the breakup with Isaac.