Also known as: Blood clot in brain
Helen Sharpe mentions recovering from an embolic stroke in the opening of the episode, indicating she has fully recovered and is returning to work.
Also known as: Colorectal cancer
Helen's mother undergoes a routine colonoscopy which reveals multiple malignant polyps that have metastasized. Dr. Sharpe delivers the terminal cancer diagnosis, creating emotional conflict between mother and daughter throughout the episode.
Also known as: Liver scarring
Isla presents with stomach pain that is diagnosed as cirrhosis caused by Alpha-1 Antitrypsin Deficiency, a genetic disorder. She requires a liver transplant, and her brother Jace is tested as a potential donor.
Also known as: Alpha-1
The underlying genetic cause of Isla's cirrhosis, which is non-alcohol related and requires liver transplantation for treatment.
Also known as: Liver scarring
Jace reveals he has severe alcoholic liver disease with 85% of his liver scarred and cirrhotic. During surgery to donate part of his liver to his sister, his remaining liver begins to die from a blood clot in the hepatic artery, but he is saved by a rare second ectopic liver.
Also known as: Low blood sugar
Darby presents with severe hypoglycemia (blood sugar of 12) causing confusion and vision loss after being given insulin instead of his prescribed growth hormone by the undertrained school secretary acting as a nurse.
Also known as: High blood sugar
Kayden, a diabetic student, develops severe hyperglycemia (blood sugar of 600) after being given growth hormone instead of his insulin by the school secretary, highlighting the dangerous consequences of inadequate school nursing.
Also known as: Stomach ulcer
After the initial hypoglycemia crisis, Darby develops bleeding from a stomach ulcer requiring emergency intervention to stop the hemorrhage.