Also known as: Huntington's disease
Angie discovers she has the Huntington's gene after genetic testing, which has been causing her to lie to her husband about wanting children. She fears passing the disease to her child and dying young, but ultimately decides to pursue pregnancy and live her remaining healthy years fully.
Also known as: MS
Marilyn has M.S. and experiences falls and flares that have inadvertently injured her daughter Tess, leading to a child protective services investigation when Cooper suspects abuse.
Also known as: Broken arm
Tess presents with arm injuries that Cooper suspects are from abuse, including a spiral fracture pattern. Eventually revealed to be accidental injury when her mother Marilyn grabbed her during an M.S.-related fall.
Also known as: Sleep disorder
Charlotte has had only three hours of sleep in three days and is experiencing severe insomnia with symptoms including aphasia and memory loss. Pete treats her with alternative medicine approaches including magnets and aromatherapy, eventually helping her sleep.
Also known as: Battered child
Cooper suspects Tess is being physically abused based on her injury pattern and calls child protective services. The case goes to court, though it's eventually revealed the injuries were accidental from her mother's M.S. falls, complicated by actual intentional hitting that Tess admits to at the hearing.
Angie and Ray initially present for fertility evaluation when they're unable to conceive. Tests show both are fertile, but Angie has been secretly preventing pregnancy due to her fear of having Huntington's disease. After testing positive for the gene, they decide to pursue pregnancy anyway.