Also known as: Ovarian cancer
Leah Hudley has stage two ovarian cancer affecting both ovaries. She refuses traditional surgery (hysterectomy/oophorectomy) because she wants to preserve her fertility and enrolls in an experimental anti-angiogenesis clinical trial instead. The trial drug causes a colonic perforation requiring emergency surgery, though the tumor appears to be shrinking.
Also known as: Thickened heart muscle
Ray 'Rocket Ray' Daniels is a retired Olympic cyclist attempting a comeback despite having hypertrophic cardiomyopathy, which caused his initial retirement. The team fixes his knee to allow him to race, but he collapses in ventricular fibrillation after winning and dies, demonstrating the fatal risk of intense exercise with this condition.
Also known as: Knee injury with fluid
Ray Daniels presents with knee pain that prevents him from racing. The team treats his knee successfully, allowing him to compete, though his underlying cardiac condition ultimately proves fatal.
Also known as: Perforated intestine
Leah develops a perforation in her descending colon as a complication of the experimental anti-angiogenesis drug, requiring emergency surgery to control life-threatening bleeding.