Also known as: Ovarian cancer
Susan has stage IV ovarian cancer with extensive metastases to liver and lymph nodes. Addison performs experimental Da Vinci robotic surgery combined with heated intraperitoneal chemotherapy to remove the tumor, which appears successful despite initially being deemed too advanced to treat.
Also known as: Head trauma
Environmental engineer Corey Ramsey crashes his car and sustains severe traumatic brain injury with multiple cerebral contusions and skull fracture. His wife initially refuses surgery to preserve his genius-level intellect, but after his pregnant girlfriend reveals herself, both women consent to life-saving surgery that will diminish his cognitive abilities.
Also known as: PTSD
Charlotte struggles with PTSD following her sexual assault, experiencing difficulty with intimacy and physical contact with Cooper. She attempts to resume sexual relations but has significant emotional difficulty, illustrating ongoing trauma recovery.