Also known as: MRKH syndrome
Nina was born without a uterus due to MRKH syndrome. The episode centers on an experimental uterine transplant procedure from her grandmother to allow her to carry a child, which ultimately fails due to surgical complications.
Also known as: Parkinson's
Laura has Parkinson's disease and increased her medication dosage, resulting in severe compulsive sexual behavior due to medication side effects on the limbic system. She refuses deep brain stimulation surgery because she enjoys the disinhibition despite infidelity and contracting gonorrhea.
Also known as: The clap
Laura contracted gonorrhea as a result of her compulsive sexual behavior caused by Parkinson's medication side effects, which she transmitted to her husband Will.
Also known as: Heart attack
Pete is recovering from a recent heart attack and quadruple bypass surgery. He struggles with insomnia, anger, and fear about mortality, and exhibits emotional disconnection from his wife Violet.
Also known as: Surgical bleeding
During Nina's experimental uterine transplant surgery, the internal iliac artery retracts causing severe hemorrhage that requires vessel embolization, ultimately leading to failure of the transplanted uterus.
Also known as: Alcoholism
Amelia is shown attending an AA meeting on day one of sobriety again after relapsing, expressing humiliation about repeated relapses after nearly a decade of sobriety.