Also known as: GBM, terminal brain cancer
Miranda, Sheldon's girlfriend with stage IV brain cancer, has a seizure at the practice and is hospitalized. The episode focuses on her declining condition as she faces end-of-life decisions, ultimately choosing to leave the hospital and spend her final days with Sheldon rather than undergo futile treatment.
Also known as: Seizure
Miranda experiences her first seizure as a complication of her brain tumor, requiring emergency intervention with lorazepam and admission for monitoring.
Also known as: PTSD
Holly, a therapy patient of Violet's for five years following a car accident that killed her parents and boyfriend, is successfully discharged from therapy after reaching all her goals. She struggles with anxiety about leaving treatment to attend culinary school in Paris but ultimately accepts she is ready to move forward.