
Also known as: Breast cancer
Male patient John is diagnosed with breast cancer with positive sentinel node biopsy, requiring chemotherapy. He is deeply embarrassed about the diagnosis and refuses to tell his family, creating a significant subplot about male pride and vulnerability.
Also known as: Twisted testicle
Turk reveals he secretly had a testicle removed due to testicular torsion after being kicked by his son. His embarrassment about the condition and resulting feelings of diminished masculinity drive a major character arc throughout the episode.
Also known as: Mono
Mentioned in passing as an example of doctor-patient confidentiality dilemma, where J.D. couldn't warn Nurse Rollins that a patient asking her out had mono, leading to transmission to her and her grandfather.