Season 2, Episode 3

Also known as: Severe dehydration

Brianna presents with syncope, hypotension, tachycardia, and severe dehydration after two days of vomiting and diarrhea. This is the initial presenting complaint that leads to discovery of her more serious conditions.

Also known as: Blood around the heart

Brianna develops cardiac tamponade with fluid buildup around her heart causing hemodynamic compromise. Conrad performs an emergent pericardiocentesis to drain the fluid and stabilize her.

Also known as: Lung scarring from silica exposure

Both John and Brianna have been inhaling silica dust from their pottery workshop for years due to poor ventilation, causing progressive lung scarring. John's condition is more advanced since he was exposed longer.

Also known as: Airway blockage

John develops acute respiratory failure requiring intubation and mechanical ventilation. His lungs show severe chronic damage that was triggered into acute crisis by volcanic ash exposure in Hawaii.

Also known as: Nocardia infection

Both patients contracted nocardia infection in Bali. John develops a characteristic rash while Brianna does not, which is more common in male patients with this infection.

Also known as: Pus in chest cavity

John's chest CT reveals empyema with pus and dead tissue in his lung requiring surgical intervention to drain and debride the infected material.

Also known as: Defibrillator malfunction

Hugh's implanted defibrillator begins misfiring, delivering inappropriate shocks. The device eventually fails completely, requiring emergency transvenous pacing and urgent replacement surgery.

Also known as: Pregnancy loss

Nic recently suffered a miscarriage, which Conrad reassures her was not her fault and nothing could have prevented it. This event is affecting both characters emotionally throughout the episode.

Also known as: Rejected transplanted liver

Brianna is a liver transplant recipient on immunosuppressive medications, with her husband John as her donor. This history makes her vulnerable to infections and complications from environmental exposures.