Also known as: CF
Eloise is a fourth-year medical student with cystic fibrosis who comes in expecting a double lung transplant, but her CF has progressed to cause liver and pancreatic failure, requiring a rare triple organ transplant (lungs, liver, and pancreas).
Also known as: Liver failure
Eloise's cystic fibrosis has caused severe liver failure with elevated liver enzymes, clotting abnormalities, and ascites requiring paracentesis, making her ineligible for lung transplant alone and necessitating inclusion of liver in the triple transplant.
Eloise's CF has caused pancreatic failure with elevated blood sugar levels, requiring pancreas inclusion in the triple transplant.
Also known as: Breathing failure
Eloise's cystic fibrosis has destroyed her lungs, causing severe respiratory failure requiring double lung transplant as part of the triple organ procedure.
Also known as: Narcotic overdose
Letty, a high school friend of Jessie's, has died from an opioid overdose and serves as the organ donor for Eloise's transplant surgery.
Also known as: Heroin addiction
Jessie has relapsed and is actively using opioids again despite recent rehab. Nic discovers she has been lying about staying sober and ultimately kicks her out after Jessie refuses to return to treatment.
During the living donor lung lobectomy, Eloise's mother Florence suffers a pulmonary artery injury with extensive damage causing life-threatening hemorrhage requiring emergency repair by Dr. Austin.
The donor lungs from Letty are found to have rare pulmonary nodules with black discoloration that were not detected during imaging, making them non-viable for transplant and forcing the team to use living donor lobes instead.