Also known as: Heart valve infection
Diana, a long-term IV heroin user, presents with endocarditis that spreads bacteria throughout her body, causing multiple splenic abscesses requiring emergency splenectomy. Her condition deteriorates into septic shock during treatment.
Also known as: Newborn heroin withdrawal
Baby Jane is born withdrawing from opiates due to her mother's heroin use during pregnancy. She exhibits discomfort, irritability, and strong crying typical of NAS.
Also known as: Spinal defect
Baby Jane is born with a neural tube defect where her lower spine did not develop properly due to lack of folic acid during pregnancy. The spinal cord and neural tissue are exposed near the skin, requiring emergency surgical repair.
Also known as: Enlarged spleen
Diana's spleen becomes massively enlarged with multiple abscesses as bacteria from her heart infection metastasizes throughout her body, requiring emergency splenectomy.
Also known as: Blood infection
Diana develops sepsis and septic shock from her endocarditis, requiring pressors and emergency surgery. Her condition deteriorates rapidly with fever, hypotension, and organ dysfunction.
Also known as: Paraneoplastic syndrome
Marty was misdiagnosed with myasthenia gravis for six years when she actually has Lambert-Eaton syndrome, a paraneoplastic condition caused by small-cell lung cancer that mimics neuromuscular symptoms but doesn't respond to myasthenia treatment.
Also known as: Small cell lung cancer
Marty's progressive muscle weakness is ultimately traced to small-cell lung cancer discovered on full body scan. The cancer is causing paraneoplastic Lambert-Eaton syndrome, explaining why her symptoms never responded to myasthenia gravis treatment.
Also known as: Brain inflammation
Baby Jane develops signs of encephalitis due to her exposed neural tissue, making the surgery more urgent to prevent catastrophic CNS infection.
Also known as: Heroin addiction
Diana is a long-term IV heroin user who continued using throughout her pregnancy. Her addiction led to endocarditis and her baby being born with NAS and a neural tube defect. She experiences painful withdrawal in the hospital.
Also known as: Drug withdrawal
Diana experiences painful opioid withdrawal after being hospitalized, exhibiting pain, agitation, and drug-seeking behavior while trying to get clean.
Also known as: A-fib
During her emergency splenectomy, Diana develops atrial fibrillation requiring cardioversion, complicating her already critical condition from sepsis.
Also known as: Heroin addiction
Dr. Sullivan exhibits signs of opioid addiction throughout the episode including dilated pupils, withdrawal symptoms, concerning behavior during surgery, erratic mood swings, and stealing a patient's urine to pass his mandatory drug test.