Also known as: Measles
Four-year-old unvaccinated child presents with fever, seizure, and altered mental status, develops classic measles rash with Koplik spots, progresses to severe pneumonia and encephalitis requiring intubation, ultimately codes and dies. Drives the episode's central medical storyline and vaccination debate.
Also known as: Fever seizure
Initial presenting symptom of the measles case, grand mal seizure at preschool with high fever leading to altered mental status.
Also known as: Lupus
Recurring character's terminal lupus flares with acute respiratory distress, elevated sed rate (84), and oxygen desaturation requiring ICU admission. He leaves AMA to attend an ordination ceremony, collapses during the service, and ultimately dies despite resuscitation attempts.
Also known as: Brain cancer
Mark undergoes his final radiation treatment but faces investigation by the Illinois Department of Professional Regulation over concerns about post-surgical cognitive competency and personality changes, particularly aphasia. This creates a major conflict as Kerry Weaver has reported him to the medical licensing board.
Also known as: End-stage lymphoma
Fifty-year-old male presents with persistent nausea, vomiting, and hypotension following chemotherapy. Becomes significant when exposed to measles while immunocompromised in the same ambulance as the measles patient.
Also known as: Difficulty finding words
Post-surgical complication from Mark's brain tumor resection affecting Broca's area, cited as one reason for the competency evaluation. Referenced as temporary and improving but used as justification for medical board investigation.