Also known as: Stage 4 lung cancer
Beatrice has metastatic disease with endobronchial mets adhering to her chest wall. The team performs surgery to excise tumor obstructing her airway for symptomatic relief, but cannot cure her. She struggles with whether to tell her daughter about her terminal diagnosis on her daughter's birthday.
Also known as: Brain cancer
Andrew, a 7th grade National Spelling Bee contestant, undergoes awake craniotomy to remove a tumor located near the language center of his brain. The surgery is successful with careful monitoring of his speech function throughout.
Also known as: Hiatal hernia
Molly Thompson's unborn baby is diagnosed with congenital diaphragmatic hernia. Addison plans to insert a scope into the uterus and inflate a balloon in the baby's airway to stimulate lung growth through minimally invasive fetal surgery.
Also known as: CHF
Denny continues his hospital stay while waiting for a heart transplant, playing Scrabble with Izzie and flirting despite his serious cardiac condition.
Also known as: Early-onset Alzheimer's
The Chief mentions to Thatcher that Ellis Grey has advanced early onset Alzheimer's disease, which is hard on Meredith. This is referenced as an ongoing condition affecting the family dynamic.