Also known as: Brain cancer
Izzie undergoes successful surgical resection of her brain tumor, but experiences postoperative complications including short-term memory impairment and difficulty forming new memories, which creates significant concern about her future ability to function independently.
Also known as: High potassium
Following her brain surgery and aggressive IL-2 treatment, Izzie develops critically elevated potassium levels (6.3) leading to uncontrollable cardiac arrhythmias and cardiac arrest at the episode's climax.
Also known as: Bus accident injuries
An unidentified patient dragged by a bus presents with catastrophic injuries including severe left forearm trauma, skull fracture, and pelvic injuries. The patient is later revealed to be George O'Malley, who pushed a woman out of the way of the bus. He undergoes multiple surgeries but dies from his injuries.
Also known as: Brain bleed
The bus trauma patient develops an epidural hematoma requiring emergent burr holes for decompression, followed by definitive surgical evacuation. Postoperative rebleeding occurs, necessitating return to the OR.
Also known as: Broken pelvis
The bus trauma patient has a severe open-book pelvic fracture causing massive internal bleeding that requires angiography for hemorrhage control and internal fixation.
Also known as: Mangled arm
The bus trauma patient sustains severe injury to the left forearm requiring complex vascular and soft tissue repair with concerns about salvaging the limb.