Also known as: Muscle death
The primary case in the episode is revealed to be House's own leg infarction caused by a clotted aneurysm. Against his wishes while in a medically induced coma, Stacy authorized surgery to remove dead muscle tissue rather than allow amputation or continuation of conservative treatment, resulting in chronic pain and disability.
Also known as: Rattlesnake bite
Teaching case disguised as a farmer with leg pain, later revealed to be a dog bite from flesh-eating bacteria. Initially treated as timber rattlesnake bite with multiple antivenoms.
Also known as: Flesh-eating bacteria
The true diagnosis of the 'farmer' case - streptococcal infection from dog bite causing rapid tissue destruction. Patient initially lied about the dog bite to protect his pet from being euthanized.
Also known as: Rhabdo
Diagnosed in the drug-seeking patient who presented with leg pain and tea-colored urine. Elevated creatine kinase indicated muscle death releasing toxic myoglobin into the kidneys.
Also known as: Bone cancer
Teaching case of 16-year-old volleyball player initially thought to have tendinitis. MRI revealed cancerous tumor on femur requiring surgical removal with possible amputation.
Also known as: Underactive thyroid
Initially diagnosed in the volleyball player via thyroid nodule found during overly thorough examination. Low T-4 confirmed hypothyroidism contributing to depression and inflammation.
Also known as: High calcium levels
Volleyball player developed elevated calcium levels (over 16) causing severe hypersensitivity to touch. Workup included ruling out parathyroid adenoma.
Also known as: Heroin addiction
Teaching case demonstrating drug-seeking behavior in a patient feigning extreme pain to obtain narcotics. Patient returned multiple times despite being identified as drug-seeking.
Also known as: Heart stopped
House experienced wide complex tachycardia progressing to cardiac arrest due to hyperkalemia from reperfusion of dead muscle tissue. Required defibrillation and was clinically dead for over a minute.
Also known as: Lead toxicity
Brief mention at end of episode of a clinic patient whose recurrent illness is caused by children playing with lead-based paint. House refuses to see the patient again.